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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169520Generated: November 1, 2026

2-[1-(4-Trifluoromethyl-phenyl)-cyclopentyl]-acetamidine hydrochloride → 2-(1-(3-Chlorophenyl)-cyclopentyl)-acetamidine hydrochloride

https://huagongshe.com/reaction/2169520

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[1-(4-Trifluoromethyl-phenyl)-cyclopentyl]-acetamidine hydrochlorideHCID 86726131—
Reactant2-(1-(3-Chlorophenyl)cyclopentyl)acetonitrileHCID 86726140—
Product2-(1-(3-Chlorophenyl)-cyclopentyl)-acetamidine hydrochlorideHCID 86726141—

Reaction Steps

2-(1-(3-Chlorophenyl)-cyclopentyl)-acetamidine hydrochloride (499) was synthesized from 2-(1-(3-chlorophenyl)cyclopentyl)acetonitrile (498) following the procedure described for HCl-salt of 2-[1-(4-trifluoromethyl-phenyl)-cyclopentyl]-acetamidine hydrochloride (242).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-49db03d5e297462c9756c981250b87eb
Source noteuspto-grants-2015_06