HRID2169529

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C1NCCn2c(CC3(c4cccc5ccccc45)CCCC3)nc(=O)c(OCc3ccccc3)c21

HCID86726013

未命名化合物

结构：O=C(c1nc(CC2(c3ccc(Cl)cc3)CCCC2)nc(O)c1OCc1ccccc1)N(CCO)Cc1ccccc1

HCID178519973

未命名化合物

PRODUCTS

生成物

结构：O=C1c2c(OCc3ccccc3)c(=O)nc(CC3(c4ccc(Cl)cc4)CCCC3)n2CCN1Cc1ccccc1

HCID86726151

未命名化合物

PROCEDURE

实验过程

This compound was prepared following the same method as described for pure 9-Benzyloxy-6-(1-naphthalen-1-yl-cyclopentylmethyl)-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (348) from N-benzyl-5-(benzyloxy)-2-((1-(4-chlorophenyl)cyclopentyl)methyl)-6-hydroxy-N-(2-hydroxyethyl)pyrimidine-4-carboxamide (507).

WORKUP

后处理

customThis compound was prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6a60ead1e82b4d6f9c822114fe18b96e
来源数据集: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09045486B2
来源说明: uspto-grants-2015_06

反应 SMILES

C(OC1C(=O)N=C(CC2(C3C4C(=CC=CC=4)C=CC=3)CCCC2)N2CCNC(=O)C=12)C1C=CC=CC=1.[CH2:37]([N:44]([CH2:75][CH2:76]O)[C:45]([C:47]1[C:52]([O:53][CH2:54][C:55]2[CH:60]=[CH:59][CH:58]=[CH:57][CH:56]=2)=[C:51]([OH:61])[N:50]=[C:49]([CH2:62][C:63]2([C:68]3[CH:73]=[CH:72][C:71]([Cl:74])=[CH:70][CH:69]=3)[CH2:67][CH2:66][CH2:65][CH2:64]2)[N:48]=1)=[O:46])[C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1>>[CH2:37]([N:44]1[CH2:75][CH2:76][N:48]2[C:49]([CH2:62][C:63]3([C:68]4[CH:69]=[CH:70][C:71]([Cl:74])=[CH:72][CH:73]=4)[CH2:64][CH2:65][CH2:66][CH2:67]3)=[N:50][C:51](=[O:61])[C:52]([O:53][CH2:54][C:55]3[CH:56]=[CH:57][CH:58]=[CH:59][CH:60]=3)=[C:47]2[C:45]1=[O:46])[C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1