HRID2169532

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CN1CCn2c(CC3(c4cccc5ccccc45)CCCC3)nc(=O)c(OCc3ccccc3)c2C1=O

HCID86726016

未命名化合物

结构：CC(C)N(CCO)C(=O)c1nc(CC2(c3cccc4ccccc34)CCCC2)nc(O)c1OCc1ccccc1

HCID178457436

未命名化合物

PRODUCTS

生成物

结构：CC(C)N1CCn2c(CC3(c4cccc5ccccc45)CCCC3)nc(=O)c(OCc3ccccc3)c2C1=O

HCID86726154

未命名化合物

PROCEDURE

实验过程

This compound was prepared following the same method as described for pure 9-Benzyloxy-2-methyl-6-(1-naphthalen-1-yl-cyclopentylmethyl)-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (352) from 5-(benzyloxy)-6-hydroxy-N-(2-hydroxyethyl)-N-isopropyl-2-((1-(naphthalen-1-yl)cyclopentyl)methyl)pyrimidine-4-carboxamide (511).

WORKUP

后处理

customThis compound was prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a86e10d1fba04663b3e0d1fa084ade46
来源数据集: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09045486B2
来源说明: uspto-grants-2015_06

反应 SMILES

C(OC1C(=O)N=C(CC2(C3C4C(=CC=CC=4)C=CC=3)CCCC2)N2CCN(C)C(=O)C=12)C1C=CC=CC=1.[CH2:38]([O:45][C:46]1[C:47]([C:69]([N:71]([CH2:75][CH2:76]O)[CH:72]([CH3:74])[CH3:73])=[O:70])=[N:48][C:49]([CH2:53][C:54]2([C:59]3[C:68]4[C:63](=[CH:64][CH:65]=[CH:66][CH:67]=4)[CH:62]=[CH:61][CH:60]=3)[CH2:58][CH2:57][CH2:56][CH2:55]2)=[N:50][C:51]=1[OH:52])[C:39]1[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=1>>[CH2:38]([O:45][C:46]1[C:51](=[O:52])[N:50]=[C:49]([CH2:53][C:54]2([C:59]3[C:68]4[C:63](=[CH:64][CH:65]=[CH:66][CH:67]=4)[CH:62]=[CH:61][CH:60]=3)[CH2:55][CH2:56][CH2:57][CH2:58]2)[N:48]2[CH2:76][CH2:75][N:71]([CH:72]([CH3:73])[CH3:74])[C:69](=[O:70])[C:47]=12)[C:39]1[CH:40]=[CH:41][CH:42]=[CH:43][CH:44]=1