2-(2-Bromoethyl)-1,3-dioxolane → HCID 86670133, compound

Participants

Reaction Steps

The title compound was prepared in a manner similar to PREPARATION x5 using (R)-2-chloro-5,6,6a,7,9,10-hexahydro-[1,4]oxazino[3,4-h]pteridine (PREPARATION x2, 250 mg, 1.103 mmol) in DMSO (7 mL), sodium tert-butoxide (127 mg, 1.324 mmol), and 2-(2-bromoethyl)-1,3-dioxolane (220 mg, 1.213 mmol) (200 mg, 56%). ESI-MS m/z [M+H]+ calc'd for C14H19ClN4O3, 327.12; found 327.2.

Provenance & Evidence