HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169715Generated: October 31, 2026
(4-Isocyanato-phenoxy)-acetic acid methyl ester → {4-[2-(4-Methoxycarbonylmethoxy-phenylcarbamoyloxy)-ethoxycarbonylamino]-phenoxy}-acetic acid methyl ester
https://huagongshe.com/reaction/2169715
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (4-Isocyanato-phenoxy)-acetic acid methyl ester | HCID 18918618 | — |
| Reactant | [4-(2-Hydroxy-ethoxycarbonylamino)-phenoxy]-acetic acid methyl ester | HCID 49764368 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | {4-[2-(4-Methoxycarbonylmethoxy-phenylcarbamoyloxy)-ethoxycarbonylamino]-phenoxy}-acetic acid methyl ester | HCID 59253986 | — |
Reaction Steps
To [4-(2-Hydroxy-ethoxycarbonylamino)-phenoxy]-acetic acid methyl ester 29 (1 g, 3.72 mmol) in toluene (10 ml) was added (4-Isocyanato-phenoxy)-acetic acid methyl ester 28 (0.8 g, 3.8 mmol) at room temperature and heated to 50° C. for 20 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | USRE045548E1 |
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| Source dataset | uspto-grants-2015_06 |
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| ORD ID | ord-16353bfb2b54479a9a94868aee6fd4e2 |
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| Source note | uspto-grants-2015_06 |
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