HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetoacetate → 3-((4-Amino-3-(ethoxycarbonyl)-2-methylquinolin-5-yl)oxy)-2,2-dimethylpropanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | Benzyl 3-(3-amino-2-cyanophenoxy)-2,2-dimethylpropanoate | HCID 66746808 | — |
| Product | 3-((4-Amino-3-(ethoxycarbonyl)-2-methylquinolin-5-yl)oxy)-2,2-dimethylpropanoic acid | HCID 66746878 | — |
Reaction Steps
Prepared as in Example 2a from benzyl 3-(3-amino-2-cyanophenoxy)-2,2-dimethylpropanoate (Example 47c) and ethyl 3-oxobutanoate as a brown solid (80%). MS 192 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09049878B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-b88d01ada1174b97a1b3944e3b2130c5 |
| Source note | uspto-grants-2015_06 |