HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2-Hydroxyethoxy)-4-methoxybenzoic acid → (S)-ethyl 4-amino-5-(2-(3-(2-hydroxyethoxy)-4-methoxybenzamido)propoxy)-2-methylquinoline-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2-Hydroxyethoxy)-4-methoxybenzoic acid | HCID 24694006 | — |
| Reactant | (S)-ethyl 4-amino-5-(2-aminopropoxy)-2-methylquinoline-3-carboxylate | HCID 86658188 | — |
| Product | (S)-ethyl 4-amino-5-(2-(3-(2-hydroxyethoxy)-4-methoxybenzamido)propoxy)-2-methylquinoline-3-carboxylate | HCID 86658195 | — |
Reaction Steps
Prepared as in Example 24a from (S)-ethyl 4-amino-5-(2-aminopropoxy)-2-methylquinoline-3-carboxylate (Example 26b) and 3-(2-hydroxyethoxy)-4-methoxybenzoic acid as a brown solid. MS 498 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09049878B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-a62957a528704f95b4ab9ba656fe9508 |
| Source note | uspto-grants-2015_06 |