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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169919Generated: October 27, 2026

3-(3-Hydroxypropoxy)-4-methoxybenzoic acid → (S)-ethyl 4-amino-5-(2-(3-(3-hydroxypropoxy)-4-methoxybenzamido)propoxy)-2-methylquinoline-3-carboxylate

https://huagongshe.com/reaction/2169919

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-Hydroxypropoxy)-4-methoxybenzoic acidHCID 59512542—
Reactant(S)-ethyl 4-amino-5-(2-aminopropoxy)-2-methylquinoline-3-carboxylateHCID 86658188—
Product(S)-ethyl 4-amino-5-(2-(3-(3-hydroxypropoxy)-4-methoxybenzamido)propoxy)-2-methylquinoline-3-carboxylateHCID 86658196—

Reaction Steps

Prepared as in Example 24a from (S)-ethyl 4-amino-5-(2-aminopropoxy)-2-methylquinoline-3-carboxylate (Example 26b) and 3-(3-hydroxypropoxy)-4-methoxybenzoic acid as a brown solid. MS 512 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09049878B2
Source datasetuspto-grants-2015_06
ORD IDord-8c62f8f1b20a4bf1bc16666d149e772b
Source noteuspto-grants-2015_06