HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetoacetate → (S)-ethyl 4-amino-5-(2-amino-3-methylbutoxy)-2-methylquinoline-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | (S)-benzyl 1-(3-amino-2-cyanophenoxy)-3-methylbutan-2-ylcarbamate | HCID 86658215 | — |
| Product | (S)-ethyl 4-amino-5-(2-amino-3-methylbutoxy)-2-methylquinoline-3-carboxylate | HCID 86658214 | — |
Reaction Steps
Prepared as in Example 2a from (S)-benzyl 1-(3-amino-2-cyanophenoxy)-3-methylbutan-2-ylcarbamate (Example 95c) and ethyl 3-oxobutanoate as brown solid (79%). MS 332 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09049878B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-ccdb2ec3dd6d4e30bd98f17082537afa |
| Source note | uspto-grants-2015_06 |