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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169953Generated: October 31, 2026

2-Amino-6-fluorobenzonitrile → N-(4-((3-Amino-2-cyanophenoxy)methyl)cyclohexyl)isonicotinamide

https://huagongshe.com/reaction/2169953

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-6-fluorobenzonitrileHCID 522659—
ReactantN-(4-(Hydroxymethyl)cyclohexyl)isonicotinamideHCID 66746905—
ProductN-(4-((3-Amino-2-cyanophenoxy)methyl)cyclohexyl)isonicotinamideHCID 66745739—

Reaction Steps

Prepared as in Example 22b from N-(4-(Hydroxymethyl)cyclohexyl)isonicotinamide (Example 108c) and 2-amino-6-fluorobenzonitrile as a colorless oil (6%). MS 351 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09049878B2
Source datasetuspto-grants-2015_06
ORD IDord-d48c87776d3d41f283d3cbc03549ae42
Source noteuspto-grants-2015_06