(-)-Menthol → HCID 66746507, compound

HRID 2169978Notes

Reaction equation

HRID 2169978 reaction equation
[CH:1]([C@@H:4]1[CH2:9][CH2:8][C@@H:7]([CH3:10])[CH2:6][C@H:5]1[OH:11])([CH3:3])[CH3:2].[NH2:12][C:13]1[C:14]([C:34]#[N:35])=[C:15]([CH:31]=[CH:32][CH:33]=1)OCC1CCN(C(OC(C)(C)C)=O)CC1>>[NH2:12][C:13]1[CH:33]=[CH:32][CH:31]=[C:15]([O:11][C@@H:5]2[CH2:6][C@H:7]([CH3:10])[CH2:8][CH2:9][C@H:4]2[CH:1]([CH3:3])[CH3:2])[C:14]=1[C:34]#[N:35]

Participants

3

Reactant 2

HCID 16666(-)-MentholHCID 66746807HCID 66746807, compound

Product 1

HCID 66746507HCID 66746507, compound

Procedure

Prepared as in Example 22b from (1R,2S,5R)-2-isopropyl-5-methylcyclohexanol and 2 as a white solid (51%). MS 273 (MH+).

Sources & evidence

ORD record
ord-fa1637c6c83c4816a66537d34338c03d
Source dataset
uspto-grants-2015_06
Patent number
US09049878B2

Reaction notes

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