Ibuprofen, (+-)- → HCID 15948295, compound

HRID 2170008Notes

Reaction equation

HRID 2170008 reaction equation
[OH:1][C:2]([CH:4]([C:6]1[CH:15]=[CH:14][C:9]([CH2:10][CH:11]([CH3:13])[CH3:12])=[CH:8][CH:7]=1)[CH3:5])=[O:3].[OH-].[Na+].O.O.O.O.O.O.[Cl-].[Sr+2:25].[Cl-]>O>[O-:3][C:2]([CH:4]([C:6]1[CH:7]=[CH:8][C:9]([CH2:10][CH:11]([CH3:12])[CH3:13])=[CH:14][CH:15]=1)[CH3:5])=[O:1].[Sr+2:25].[O-:3][C:2]([CH:4]([C:6]1[CH:7]=[CH:8][C:9]([CH2:10][CH:11]([CH3:12])[CH3:13])=[CH:14][CH:15]=1)[CH3:5])=[O:1]

Participants

5

Reactant 3

HCID 3672Ibuprofen, (+-)-HCID 14798Sodium HydroxideHCID 610186810025-70-4

Product 1

HCID 15948295HCID 15948295, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

Ibuprofen (2.59 g, 12.5 mmol) was dissolved in water (100 ml) containing sodium hydroxide (0.503 g, 12.5 mmol). A solution of strontium chloride hexahydrate (1.68 g, 6.3 mmol) in water (5 ml) was added. The mixture was stirred for 10 minutes at room temperature and the title compound was isolated by filtration and dried. Yield 1.30 g (44%). Melting point>300.degree. C.

Sources & evidence

ORD record
ord-27849d9ff56a4ceb92c3ad2c871b5646
Source dataset
uspto-grants-2015_06
Patent number
US09050312B2

Reaction notes

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