HCID 71201955, compound → HCID 71201954, compound

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Reaction Steps

Prepared analogously to Compound 46 using Compound 45. Yield=343 mg (20%) as a solid. 1H NMR (400 MHz, COCl3): δ8.10-8.11 (d, J=2.4 Hz, 1H), 7.54-7.57 (m, 1H), 7.25-7.29 (m, 2H), 7.18-7.21 (m, 1H), 7.05-7.07 (m, 2H), 6.66-6.88 (t, J=4.2 Hz, 1H), 6.38-4.40 (d, J=7.2 Hz, 1H), 5.20-5.21 (m, 1H), 5.10-5.12 (m, 1H), 3.94-3.99 (m, 2H), 3.57-3.69 (m, 4H), 3.37 (s, 3H), 2.42-2.49 (m, 1H), 2.02-2.08 (m, 2H), 1.61-1.79 (m, 4H), 1.25-1.28 (m, 1H) [α]D20=159.3 (c=0.198 g/100 mL, CHCl3). LC-MS (m/z) 383.15 (MH+), tR=0.54 min (method B).

Provenance & Evidence