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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2170115Generated: November 1, 2026

Benzyl 3-(4-hydroxyphenyl)propanoate → 3-(4-tert-Butoxycarbonylmethoxy-phenyl)-propionic acid benzyl ester

https://huagongshe.com/reaction/2170115

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl 3-(4-hydroxyphenyl)propanoateHCID 14211262—
Reactant3-(4-tert-Butoxycarbonylmethoxy-3-chloro-phenyl)-propionic acid benzyl esterHCID 66797513—
Product3-(4-tert-Butoxycarbonylmethoxy-phenyl)-propionic acid benzyl esterHCID 66798017—

Reaction Steps

This compound was prepared analogously to 3-(4-tert-butoxycarbonylmethoxy-3-chloro-phenyl)-propionic acid benzyl ester (Int. B step 2) by replacing 3-(3-chloro-4-hydroxy-phenyl)-propionic acid benzyl ester with 3-(4-hydroxy-phenyl)-propionic acid benzyl ester (commercially available).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09050339B2
Source datasetuspto-grants-2015_06
ORD IDord-40a2b2a68ff24c9cbf2a929269d6f9de
Source noteuspto-grants-2015_06