HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Cyanopyridine → N-(pyridin-3-ylmethyl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Cyanopyridine | HCID 79 | — |
| Reactant | Aniline | HCID 6115 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Rhodium | HCID 23948 | — |
| Product | N-(pyridin-3-ylmethyl)aniline | HCID 1082702 | — |
Reaction Steps
A mixture of 3-cyanopyridine (10.4 g), aniline (101.8 g) and a 5% rhodium on carbon catalyst (1.0 g) was treated with hydrogen at 60 psig 30 deg C. for 13 hours in a rocking autoclave. The catalyst was removed by filtration and the filtrate analyzed by glc to show 3.7 g of N-phenyl-N-(3-pyridylmethyl)amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05424436 |
| Source dataset | uspto-grants-1995_06 |
| ORD ID | ord-2dc1b1df31414fdabba8d25b8bcdf139 |
| Source note | uspto-grants-1995_06 |