Hydrochloric Acid → HCID 90280247, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 55C (750 mg, 3.03 mmol) in THF at 78° C., DIBAL-H (3.33 mL, 3.33 mmol) in toluene was added to the solution slowly. Then, it was stirred for 2 hours at 78° C. HCl (4 mL, 1 N) was added to the solution and warmed to 0° C. The mixture was stirred for 20 minutes at 0° C. then extracted with EtOAc twice. The organic layer was dried and concentrated to provide the crude product which was used without further purification. MS (m/z) 189 [M+H]+.

Provenance & Evidence