HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethyl phosphite → Benzyl (diethoxyphosphoryl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethyl phosphite | HCID 31215 | — |
| Reactant | Benzyl bromoacetate | HCID 62576 | — |
| Product | Benzyl (diethoxyphosphoryl)acetate | HCID 281239 | 80.3% |
Reaction Steps
The mixture of bromo-acetic acid benzyl ester (229 g, 1.0 mol) and phosphorous acid triethyl ester (166 g, 1.0 mol) was stirred at reflux for 10 hrs and the solvent was evaporated in vacuo to give crude (diethoxy-phosphoryl)-acetic acid benzyl ester (230 g) which was directly used for next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09051280B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-74ab55953b9748ec8c6d2eb897d01782 |
| Source note | uspto-grants-2015_06 |