HCID 71007959, compound → HCID 71008349, compound

Participants

Reaction Steps

The mixture of (1-benzyl-7-methoxy-3,4-dihydro-naphthalen-2-yl)-acetic acid benzyl ester (102 g, 0.26 mol) and Pd(OH)2/C (30 g) in EtOH (5 L) was stirred under H2 (30 psi) atmosphere overnight, then the solution was filtered to removed the solid and concentrated to give crude product, recrystallized from DCM to give (1-benzyl-7-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-acetic acid (60 g, yield 74%) as white solid.

Provenance & Evidence