HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cumylamine → HCID 50904175, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cumylamine | HCID 68509 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Reactant | HCID 63749119 | HCID 63749119 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 50904175 | HCID 50904175 | — |
Reaction Steps
To a solution of 1-(2,4-difluorobenzyl)-1H-indole-5-carboxylic acid (50 mg, 0.17 mmol, 1 equiv) in DCM (2 mL) was added 2-phenylpropane-2-amine (27 μL, 0.18 mmol, 1.05 equiv), DIEA (30 μL, 0.17 mmol, 1 equiv) and HATU (68 mg, 0.18 mmol, 1.05 equiv). The reaction mixture was stirred 2 h at room temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09051265B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-0942d5536f9a4ad5969408a1bca506e4 |
| Source note | uspto-grants-2015_06 |