1-Chloro-3-(2-chloroethyl)benzene → HCID 71075582, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:8][CH2:9]Cl)[CH:5]=[CH:6][CH:7]=1.[C:11]1([CH:17]([NH:20][C:21]([C:23]2[CH:24]=[C:25]3[C:29](=[CH:30][CH:31]=2)[NH:28][CH:27]=[CH:26]3)=[O:22])[CH2:18][CH3:19])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:6][CH:7]=1)[CH2:8][CH2:9][N:28]1[C:29]2[C:25](=[CH:24][C:23]([C:21]([NH:20][CH:17]([C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=3)[CH2:18][CH3:19])=[O:22])=[CH:31][CH:30]=2)[CH:26]=[CH:27]1Participants
3
Procedure
The title compound was prepared following the same general protocol as described in Step 1 of Example 21, using 2-(3-chlorophenyl)ethyl chloride and N-(1-phenylpropyl)-1H-indole-5-carboxamide. LC-MS 417 (M+H).
Sources & evidence
- ORD record
- ord-a9adc79c5a3a49069717e6fe6a40961d
- Source dataset
- uspto-grants-2015_06
- Patent number
- US09051265B2
Reaction notes
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