2,3-Difluorobenzoyl chloride → HCID 71075355, compound

HRID 2170613Notes

Reaction equation

HRID 2170613 reaction equation
[F:1][C:2]1[C:10]([F:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4](Cl)=[O:5].[C:12]1([CH:18]([NH:21][C:22]([C:24]2[CH:25]=[C:26]3[C:30](=[CH:31][CH:32]=2)[NH:29][CH:28]=[CH:27]3)=[O:23])[CH2:19][CH3:20])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[F:1][C:2]1[C:10]([F:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([N:29]1[C:30]2[C:26](=[CH:25][C:24]([C:22]([NH:21][CH:18]([C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=3)[CH2:19][CH3:20])=[O:23])=[CH:32][CH:31]=2)[CH:27]=[CH:28]1)=[O:5]

Participants

3

Reactant 2

HCID 5195492,3-Difluorobenzoyl chlorideHCID 63717133HCID 63717133, compound

Product 1

HCID 71075355HCID 71075355, compound

Procedure

The title compound was prepared following the same general protocol as described in Example 25, using 2,3-difluorobenzoylchloride and N-(1-phenylpropyl)-1H-indole-5-carboxamide. LC-MS 419 (M+H).

Sources & evidence

ORD record
ord-ee9dc19bfd4b4a1184990bf0d80022da
Source dataset
uspto-grants-2015_06
Patent number
US09051265B2

Reaction notes

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