5-(Bromomethyl)-2-chloropyridine → HCID 71478926, compound
Reaction equation
Br[CH2:2][C:3]1[CH:4]=[CH:5][C:6]([Cl:9])=[N:7][CH:8]=1.[C:10]1([CH:16]([NH:19][C:20]([C:22]2[CH:23]=[C:24]3[C:28](=[CH:29][CH:30]=2)[NH:27][CH:26]=[CH:25]3)=[O:21])[CH2:17][CH3:18])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[Cl:9][C:6]1[N:7]=[CH:8][C:3]([CH2:2][N:27]2[C:28]3[C:24](=[CH:23][C:22]([C:20]([NH:19][CH:16]([C:10]4[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=4)[CH2:17][CH3:18])=[O:21])=[CH:30][CH:29]=3)[CH:25]=[CH:26]2)=[CH:4][CH:5]=1Participants
3
Procedure
The title compound was prepared following the same general protocol as described in Step 1, Example 21, using 5-(bromomethyl)-2-chloropyridine and N-(1-phenylpropyl)-1H-indole-5-carboxamide. LC-MS 404 (M+H).
Sources & evidence
- ORD record
- ord-67308701ec1349be8731b159d2d9ce84
- Source dataset
- uspto-grants-2015_06
- Patent number
- US09051265B2
Reaction notes
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