HCID 71075728, compound → HCID 86674588, compound

HRID 2170656Notes

Reaction equation

HRID 2170656 reaction equation
[Br:1][CH2:2][C:3]1[CH:4]=[CH:5][C:6](Cl)=[C:7]([CH:15]=1)[O:8][C@@H:9]([CH3:14])[C:10]([O:12][CH3:13])=[O:11].[Cl:17]C1C=CC(O[C@@H](C)C(OC)=O)=CC=1C>>[Br:1][CH2:2][C:3]1[CH:15]=[C:7]([CH:6]=[CH:5][C:4]=1[Cl:17])[O:8][C@@H:9]([CH3:14])[C:10]([O:12][CH3:13])=[O:11]

Participants

3

Reactant 2

HCID 71075728HCID 71075728, compoundHCID 86674584HCID 86674584, compound

Product 1

HCID 86674588HCID 86674588, compound

Procedure

The title compound was prepared following the same general protocol as described for the synthesis of the (S)-methyl 2-(5-(bromomethyl)-2-chlorophenoxy)propanoate (Step 2, Example 55), using the (S)-methyl 2-(4-chloro-3-methylphenoxy)propanoate instead of the (S)-methyl 2-(2-chloro-5-methylphenoxy)propanoate.

Sources & evidence

ORD record
ord-53cfc03600f348538a784bc509d9ea90
Source dataset
uspto-grants-2015_06
Patent number
US09051265B2

Reaction notes

Loading…