HCID 27187797, compound → HCID 86674589, compound

HRID 2170699Notes

Reaction equation

HRID 2170699 reaction equation
Br[CH2:2][C:3]1[CH:4]=[C:5]([C:9]([CH3:13])([CH3:12])[C:10]#[N:11])[CH:6]=[CH:7][CH:8]=1.[CH3:14][C:15]1[NH:16][C:17]2[C:22]([C:23]=1[CH3:24])=[CH:21][C:20]([C:25]([O:27][CH2:28][CH:29]=[CH2:30])=[O:26])=[CH:19][CH:18]=2>>[C:10]([C:9]([C:5]1[CH:4]=[C:3]([CH:8]=[CH:7][CH:6]=1)[CH2:2][N:16]1[C:17]2[C:22](=[CH:21][C:20]([C:25]([O:27][CH2:28][CH:29]=[CH2:30])=[O:26])=[CH:19][CH:18]=2)[C:23]([CH3:24])=[C:15]1[CH3:14])([CH3:13])[CH3:12])#[N:11]

Participants

3

Reactant 2

HCID 27187797HCID 27187797, compoundHCID 86674590HCID 86674590, compound

Product 1

HCID 86674589HCID 86674589, compound

Procedure

The title compound was prepared following the same general protocol as described in Step 2, Example 1, using 2-(3-(bromomethyl)phenyl)-2-methylpropanenitrile and allyl 2,3-dimethyl-1H-indole-5-carboxylate. ESI-MS (m/z): 387 [M+H]+.

Sources & evidence

ORD record
ord-1c285e35cd71488caf926db770f77c74
Source dataset
uspto-grants-2015_06
Patent number
US09051265B2

Reaction notes

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