HCID 71075610, compound → HCID 71075867, compound

HRID 2170701Notes

Reaction equation

HRID 2170701 reaction equation
Cl.[CH:2]1([C:5]2[CH:6]=[C:7]([C@@H:11]([NH2:13])[CH3:12])[CH:8]=[CH:9][CH:10]=2)[CH2:4][CH2:3]1.[C:14]([C:16]([C:19]1[CH:20]=[C:21]([CH:37]=[CH:38][CH:39]=1)[CH2:22][N:23]1[C:31]2[C:26](=[CH:27][C:28]([C:32](O)=[O:33])=[CH:29][CH:30]=2)[C:25]([CH3:35])=[C:24]1[CH3:36])([CH3:18])[CH3:17])#[N:15]>>[C:14]([C:16]([C:19]1[CH:20]=[C:21]([CH:37]=[CH:38][CH:39]=1)[CH2:22][N:23]1[C:31]2[C:26](=[CH:27][C:28]([C:32]([NH:13][C@H:11]([C:7]3[CH:8]=[CH:9][CH:10]=[C:5]([CH:2]4[CH2:4][CH2:3]4)[CH:6]=3)[CH3:12])=[O:33])=[CH:29][CH:30]=2)[C:25]([CH3:35])=[C:24]1[CH3:36])([CH3:18])[CH3:17])#[N:15]

Participants

3

Reactant 2

HCID 71075610HCID 71075610, compoundHCID 86674582HCID 86674582, compound

Product 1

HCID 71075867HCID 71075867, compound

Procedure

The title compound was prepared following the same general protocol as described in Step 4, Example 1, using (S)-1-(3-cyclopropylphenyl)ethanamine hydrochloride and 1-(3-(2-cyanopropan-2-yl)benzyl)-2,3-dimethyl-1H-indole-5-carboxylic acid. ESI-MS (m/z): 490 [M+H]+.

Sources & evidence

ORD record
ord-75962411a6b64e778de353fbedf61957
Source dataset
uspto-grants-2015_06
Patent number
US09051265B2

Reaction notes

Loading…