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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2170715Generated: October 30, 2026

Sodium Hydroxide → HCID 71075509, compound

https://huagongshe.com/reaction/2170715

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 71075736HCID 71075736—
SolventMethanolHCID 887—
SolventDimethylformamideHCID 6228—
ProductHCID 71075509HCID 71075509—

Reaction Steps

A solution of (2S)-methyl 2-(4-(1-(5-(((S)-1-(4-(tert-butyl)phenyl)ethyl)carbamoyl)-2,3-dimethyl-1H-indol-1-yl)ethyl)phenoxy)propanoate (˜0.07 mmol) and NaOH (2 M, 0.2 mL) in MeOH (2 mL) and DMF (1 mL) was stirred at rt for 5 h. It was neutralized and purified by preparative HPLC to yield the title compound as a white solid. ESI-MS (m/z): 541 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09051265B2
Source datasetuspto-grants-2015_06
ORD IDord-fe90e903da7c42e9877e7df1282e74f8
Source noteuspto-grants-2015_06