HCID 27187797, compound → HCID 86674597, compound

HRID 2170717Notes

Reaction equation

HRID 2170717 reaction equation
Br[CH2:2][C:3]1[CH:4]=[C:5]([C:9]2([C:12]#[N:13])[CH2:11][CH2:10]2)[CH:6]=[CH:7][CH:8]=1.[CH3:14][C:15]1[NH:16][C:17]2[C:22]([C:23]=1[CH3:24])=[CH:21][C:20]([C:25]([O:27][CH2:28][CH:29]=[CH2:30])=[O:26])=[CH:19][CH:18]=2>>[C:12]([C:9]1([C:5]2[CH:4]=[C:3]([CH:8]=[CH:7][CH:6]=2)[CH2:2][N:16]2[C:17]3[C:22](=[CH:21][C:20]([C:25]([O:27][CH2:28][CH:29]=[CH2:30])=[O:26])=[CH:19][CH:18]=3)[C:23]([CH3:24])=[C:15]2[CH3:14])[CH2:11][CH2:10]1)#[N:13]

Participants

3

Reactant 2

HCID 27187797HCID 27187797, compoundHCID 86674598HCID 86674598, compound

Product 1

HCID 86674597HCID 86674597, compound

Procedure

The title compound was prepared following the same general protocol as described in Step 2, Example 1, using 1-(3-(bromomethyl)phenyl)cyclopropanecarbonitrile and allyl 2,3-dimethyl-1H-indole-5-carboxylate.

Sources & evidence

ORD record
ord-e72d3deda6a04657953633a668d16b15
Source dataset
uspto-grants-2015_06
Patent number
US09051265B2

Reaction notes

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