HCID 71075333, compound → HCID 71075587, compound

HRID 2170719Notes

Reaction equation

HRID 2170719 reaction equation
[C:1]([C:3]1([C:6]2[CH:7]=[C:8]([CH:24]=[CH:25][CH:26]=2)[CH2:9][N:10]2[C:18]3[C:13](=[CH:14][C:15]([C:19](O)=[O:20])=[CH:16][CH:17]=3)[C:12]([CH3:22])=[C:11]2[CH3:23])[CH2:5][CH2:4]1)#[N:2].[CH:27]1([C:30]2[CH:31]=[C:32]([C@@H:36]([NH2:38])[CH3:37])[CH:33]=[CH:34][CH:35]=2)[CH2:29][CH2:28]1>>[C:1]([C:3]1([C:6]2[CH:7]=[C:8]([CH:24]=[CH:25][CH:26]=2)[CH2:9][N:10]2[C:18]3[C:13](=[CH:14][C:15]([C:19]([NH:38][C@H:36]([C:32]4[CH:33]=[CH:34][CH:35]=[C:30]([CH:27]5[CH2:29][CH2:28]5)[CH:31]=4)[CH3:37])=[O:20])=[CH:16][CH:17]=3)[C:12]([CH3:22])=[C:11]2[CH3:23])[CH2:5][CH2:4]1)#[N:2]

Participants

3

Reactant 2

HCID 71075333HCID 71075333, compoundHCID 86674583(αS)-3-Cyclopropyl-α-methylbenzenemethanamine

Product 1

HCID 71075587HCID 71075587, compound

Procedure

The title compound was prepared following the same general protocol as described in Step 5, Example 35, using 1-(3-(1-cyanocyclopropyl)benzyl)-2,3-dimethyl-1H-indole-5-carboxylic acid and (S)-1-(3-cyclopropylphenyl)ethanamine.

Sources & evidence

ORD record
ord-e39050ef83ef4edaacf917898bc6a9e2
Source dataset
uspto-grants-2015_06
Patent number
US09051265B2

Reaction notes

Loading…