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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2170723Generated: October 30, 2026

Sodium Hydroxide → HCID 71075453, compound

https://huagongshe.com/reaction/2170723

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 71099832HCID 71099832—
SolventDimethyl SulfoxideHCID 679—
SolventMethanolHCID 887—
ProductHCID 71075453HCID 71075453—

Reaction Steps

A solution of (S)-Methyl 3-((5-((1-(3-cyclopropylphenyl)ethyl)carbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)benzoate (˜0.07 mmol) and NaOH (2 M, 0.5 mL) in MeOH (2 mL) and DMSO (1 mL) was stirred at rt for 15 h. It was neutralized and purified by preparative HPLC to yield the title compound as a white solid. ESI-MS (m/z): 467 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09051265B2
Source datasetuspto-grants-2015_06
ORD IDord-4afbe8cd72554817ac22763daf2c2e5a
Source noteuspto-grants-2015_06