3-Ethoxythiophenol → HCID 67169334, compound

HRID 2170846Notes

Reaction equation

HRID 2170846 reaction equation
CS(O[CH:6]1[CH2:11][CH2:10][N:9]([C:12]([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:13])[CH2:8][CH2:7]1)(=O)=O.[CH2:19]([O:21][C:22]1[CH:23]=[C:24]([SH:28])[CH:25]=[CH:26][CH:27]=1)[CH3:20]>>[CH2:19]([O:21][C:22]1[CH:23]=[C:24]([S:28][CH:6]2[CH2:7][CH2:8][N:9]([C:12]([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:13])[CH2:10][CH2:11]2)[CH:25]=[CH:26][CH:27]=1)[CH3:20]

Participants

3

Reactant 2

HCID 27363503-EthoxythiophenolHCID 41848691-(tert-Butoxycarbonyl)-4-(methanesulfonyloxy)piperidine

Product 1

HCID 67169334HCID 67169334, compoundYield 67%

Procedure

The title compound was prepared in 67% yield (1.29 g, yellow oil) from tert-butyl 4-((methylsulfonyl)oxy)piperidine-1-carboxylate (1.60 g, 5.73 mmol) and 3-ethoxybenzenethiol (1.06 g, 6.87 mmol) by the similar manner in Step-1 of Intermediate-4.

Sources & evidence

ORD record
ord-ae591dbabb2c435e9d0e7c0503dab6f8
Source dataset
uspto-grants-2015_06
Patent number
US09051296B2

Reaction notes

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