HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → 11-iodoundecanoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | 11-Bromoundecanoic acid | HCID 17812 | — |
| Solvent | Water | HCID 962 | — |
| Product | 11-iodoundecanoic Acid | HCID 11461104 | — |
Reaction Steps
11-Iodo undecanoic acid was synthesized according to Bergbreiter, J. Org. Chem., 40 (6), (1975) 779-782. Briefly, 250 g 11-Bromo undecanoic acid, 325 g Sodium iodide and 2 liter acetone were refluxed under N2 atmosphere for 24 hours. The mixture was divided and added to 4 liter H2O each. The mixtures were fritted and the crude product recrystallized from methanol and finally characterized by the melting point.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08193246B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-24c6385fa7a54629aa097cd66d63737e |
| Source note | uspto-grants-2012_06 |