O-ethylhydroxylamine hydrochloride → HCID 86654648, compound

HRID 2170883Notes

Reaction equation

HRID 2170883 reaction equation
[OH:1][CH:2]([CH:6]([NH:14][C:15](=[O:33])[C:16]1[CH:21]=[CH:20][CH:19]=[N:18][C:17]=1[N:22]1[CH:26]=[CH:25][C:24]([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)=[N:23]1)[CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:3](O)=[O:4].Cl.[CH2:35]([O:37][NH2:38])[CH3:36]>>[CH2:35]([O:37][NH:38][C:3](=[O:4])[CH:2]([OH:1])[CH:6]([NH:14][C:15](=[O:33])[C:16]1[CH:21]=[CH:20][CH:19]=[N:18][C:17]=1[N:22]1[CH:26]=[CH:25][C:24]([C:27]2[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=2)=[N:23]1)[CH2:7][C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1)[CH3:36]

Participants

3

Reactant 2

HCID 76850O-ethylhydroxylamine hydrochlorideHCID 672381942-hydroxy-4-phenyl-3-(2-(3-phenyl-1H-pyrazol-1-yl)nicotinamido)butanoic acid

Product 1

HCID 86654648HCID 86654648, compound

Procedure

The reaction was carried out in analogy to reaction step 1.3 by reacting 2-hydroxy-4-phenyl-3-(2-(3-phenyl-1H-pyrazol-1-yl)nicotinamido)butanoic acid with O-ethylhydroxylamine hydrochloride. ESI-MS [M+H]+: 486.2

Workup

  1. customThe reaction was carried out in analogy to reaction step 1.3

Sources & evidence

ORD record
ord-7b12397b68f248a0a5a424d09906e7ef
Source dataset
uspto-grants-2015_06
Patent number
US09051304B2

Reaction notes

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