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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2170897Generated: October 30, 2026

(R)-1-(2-fluorobenzyl)-5-oxopyrrolidine-2-carboxylic acid → Ethyl 3-((R)-1-(2-fluorobenzyl)-5-oxopyrrolidine-2-carboxamido)-2-hydroxy-4-phenylbutanoate

https://huagongshe.com/reaction/2170897

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-1-(2-fluorobenzyl)-5-oxopyrrolidine-2-carboxylic acidHCID 42127382—
ReactantHCID 86644788HCID 86644788—
ProductEthyl 3-((R)-1-(2-fluorobenzyl)-5-oxopyrrolidine-2-carboxamido)-2-hydroxy-4-phenylbutanoateHCID 67095178—

Reaction Steps

The reaction was carried out in analogy to reaction step 1.1 by reacting (R)-1-(2-fluorobenzyl)-5-oxopyrrolidine-2-carboxylic acid and 4-ethoxy-3-hydroxy-4-oxo-1-phenylbutan-2-aminium chloride. ESI-MS [M+H]+=443.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09051304B2
Source datasetuspto-grants-2015_06
ORD IDord-c254f8a37452494cb25f7bb0f0d7a848
Source noteuspto-grants-2015_06