HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 71279801, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Methoxyethyl chloroformate | HCID 69400 | — |
| Reactant | HCID 71279377 | HCID 71279377 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 71279801 | HCID 71279801 | — |
Reaction Steps
To a stirring solution of 4-[2-(1-Aminomethyl-cyclopropylmethoxy)-3,4-dimethoxy-phenyl]-indan-1-one (Compound 182) (150 mg, 0.272 mmol) in dichloromethane (10 mL), were added triethylamine (0.082 g, 0.811 mmol) and 2-methoxyethyl carbonochloridate (68 mg, 0.544 mmol) and the resultant reaction mixture was subjected to the conditions used in the preparation of Compound 183 to afford the title compound as a solid
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09051290B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-e960c5f6a33d43b699af65e1287482ef |
| Source note | uspto-grants-2015_06 |