3,4-Difluorobenzaldehyde → 3-Fluoro-4-((5-(trifluoromethyl)pyridin-3-yl)oxy)benzaldehyde

HRID 2171349Notes

Reaction equation

HRID 2171349 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1F)[CH:5]=[O:6].[F:11][C:12]([F:21])([F:20])[C:13]1[CH:14]=[C:15]([OH:19])[CH:16]=[N:17][CH:18]=1>>[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[O:19][C:15]1[CH:16]=[N:17][CH:18]=[C:13]([C:12]([F:21])([F:11])[F:20])[CH:14]=1)[CH:5]=[O:6]

Participants

3

Reactant 2

HCID 5880883,4-DifluorobenzaldehydeHCID 229897075-(Trifluoromethyl)pyridin-3-ol

Product 1

HCID 867283273-Fluoro-4-((5-(trifluoromethyl)pyridin-3-yl)oxy)benzaldehyde

Procedure

The title compound was prepared by a procedure similar to that described for D30 starting from 3,4-difluorobenzaldehyde and 5-(trifluoromethyl)pyridin-3-ol.

Sources & evidence

ORD record
ord-89dae0e485224e36a047cbb2d20b43c8
Source dataset
uspto-grants-2015_06
Patent number
US09051325B2

Reaction notes

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