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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2171365Generated: October 31, 2026

3,4-Difluorobenzyl alcohol → 7-((3,4-difluorobenzyl)oxy)-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one

https://huagongshe.com/reaction/2171365

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-Difluorobenzyl alcoholHCID 522833—
Reactant7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728314—
Product7-((3,4-difluorobenzyl)oxy)-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728337—

Reaction Steps

The title compound was prepared by a procedure similar to that described for E1 starting from 7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one and (3,4-dif-luorophenyl)methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09051325B2
Source datasetuspto-grants-2015_06
ORD IDord-292c812d4f5d48538e6f989463f7e146
Source noteuspto-grants-2015_06