2-Thiopheneethanol → HCID 86728344, compound
Reaction equation
Cl[C:2]1[CH:3]=[C:4]2[N:11]([CH3:12])[C:10]([CH3:14])([CH3:13])[CH2:9][N:5]2[C:6](=[O:8])[N:7]=1.[S:15]1[CH:19]=[CH:18][CH:17]=[C:16]1[CH2:20][CH2:21][OH:22]>>[CH3:12][N:11]1[C:4]2[N:5]([C:6](=[O:8])[N:7]=[C:2]([O:22][CH2:21][CH2:20][C:16]3[S:15][CH:19]=[CH:18][CH:17]=3)[CH:3]=2)[CH2:9][C:10]1([CH3:14])[CH3:13]Participants
3
Procedure
The title compound was prepared by a procedure similar to that described for E1 starting from 7-chloro-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one and 2-(thiophen-2-yl)ethanol.
Sources & evidence
- ORD record
- ord-3f1d3cb36c9b4b348f4bf4912694cb75
- Source dataset
- uspto-grants-2015_06
- Patent number
- US09051325B2
Reaction notes
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