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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2171375Generated: October 25, 2026

(4-((6-Chloropyridin-3-yl)oxy)-3-fluorophenyl)methanol → 7-((4-((6-chloropyridin-3-yl)oxy)-3-fluorobenzyl)oxy)-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one

https://huagongshe.com/reaction/2171375

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-((6-Chloropyridin-3-yl)oxy)-3-fluorophenyl)methanolHCID 86676396—
Reactant7-chloro-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728345—
Product7-((4-((6-chloropyridin-3-yl)oxy)-3-fluorobenzyl)oxy)-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728350—

Reaction Steps

The title compound was prepared by a procedure similar to that described for E9 starting from (4-((6-chloropyridin-3-yl)oxy)-3-fluorophenyl)methanol and 7-chloro-1,2,2-trimet-hyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09051325B2
Source datasetuspto-grants-2015_06
ORD IDord-7c940e66e8934710a7883167b86ed1dc
Source noteuspto-grants-2015_06