(4-(4-Chloro-3-(trifluoromethyl)phenoxy)phenyl)methanol → HCID 86728354, compound

HRID 2171378Notes

Reaction equation

HRID 2171378 reaction equation
[Cl:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][C:7]2[CH:12]=[CH:11][C:10]([CH2:13][OH:14])=[CH:9][CH:8]=2)=[CH:4][C:3]=1[C:17]([F:20])([F:19])[F:18].Cl[C:22]1[CH:23]=[C:24]2[N:31]([CH:32]3[CH2:34][CH2:33]3)[CH2:30][CH2:29][N:25]2[C:26](=[O:28])[N:27]=1>>[Cl:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][C:7]2[CH:12]=[CH:11][C:10]([CH2:13][O:14][C:22]3[CH:23]=[C:24]4[N:31]([CH:32]5[CH2:34][CH2:33]5)[CH2:30][CH2:29][N:25]4[C:26](=[O:28])[N:27]=3)=[CH:9][CH:8]=2)=[CH:4][C:3]=1[C:17]([F:18])([F:19])[F:20]

Participants

3

Reactant 2

HCID 66825563(4-(4-Chloro-3-(trifluoromethyl)phenoxy)phenyl)methanolHCID 86728325HCID 86728325, compound

Product 1

HCID 86728354HCID 86728354, compound

Procedure

The title compound was prepared by a procedure similar to that described for E9 starting from (4-(4-chloro-3-(trifluoromethyl)phenoxy)phenyl)methanol and 7-chloro-1-cyclopropyl-2,3-dihydroimi-dazo[1,2-c]pyrimidin-5(1H)-one.

Sources & evidence

ORD record
ord-4d1817ce4cdf4fd2a69853452c9ba7ca
Source dataset
uspto-grants-2015_06
Patent number
US09051325B2

Reaction notes

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