HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Bromide → 6-Amino-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-quinazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Bromide | HCID 253877 | — |
| Reactant | Chloroform methanol | HCID 21584188 | — |
| Reactant | 6-Amino-2-(3,4-methylendioxy-phenyl)quinazoline | HCID 44140427 | — |
| Product | 6-Amino-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-quinazoline | HCID 57863165 | 67% |
Reaction Steps
This compound was synthesized in 67% yield, according to the procedure described in example 3 for 6-amino-2-(3,4-methylendioxy-phenyl)-quinazoline. C16H13N3O2, MW: 279.30. mp 179.4-181.6° C.; 1H NMR (DMSO-d6) 9.24 (s, 1H), 7.92-7.98 (m, 2H), 7.72 (d, 1H), 7.38 (dd, 1H), 6.89-6.99 (m, 2H), 5.91 (s, 2H), 4.31 (s, 4H); IR (KBr) 1555, 1507, 1286; TLC (CHCl3/MeOH 9/1) Rf=0.65.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08193353B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-6d13d74f20a74c1ea247e7705c20082d |
| Source note | uspto-grants-2012_06 |