HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(2-Fluoro-4-(hydroxymethyl)phenoxy)nicotinonitrile → (S)-5-(4-(((1,2-dimethyl-5-oxo-1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidin-7-yl)ox-y)methyl)-2-fluorophenoxy)nicotinonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(2-Fluoro-4-(hydroxymethyl)phenoxy)nicotinonitrile | HCID 66826150 | — |
| Reactant | (S)-7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one | HCID 86728322 | — |
| Product | (S)-5-(4-(((1,2-dimethyl-5-oxo-1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidin-7-yl)ox-y)methyl)-2-fluorophenoxy)nicotinonitrile | HCID 86728360 | — |
Reaction Steps
The title compound was prepared by a procedure similar to that described for E9 starting from 5-(2-fluoro-4-(hydroxymethyl)phenoxy)nicotinonitrile and (S)-7-chloro-1,2-dimet-hyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09051325B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-b2fe6436569c43f892ed711ae07b6ff0 |
| Source note | uspto-grants-2015_06 |