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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2171386Generated: October 31, 2026

(3-Fluoro-4-(3-fluorophenoxy)phenyl)methanol → (S)-7-((3-fluoro-4-(3-fluorophenoxyl)benzyl)oxy)-1,2-dimethyl-2,3-dihydroimidazo-[1,2-c]pyrimidin-5(1H)-one

https://huagongshe.com/reaction/2171386

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Fluoro-4-(3-fluorophenoxy)phenyl)methanolHCID 28946122—
Reactant(S)-7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728322—
Product(S)-7-((3-fluoro-4-(3-fluorophenoxyl)benzyl)oxy)-1,2-dimethyl-2,3-dihydroimidazo-[1,2-c]pyrimidin-5(1H)-oneHCID 86728361—

Reaction Steps

The title compound was prepared by a procedure similar to that described for E9 starting from (3-fluoro-4-(3-fluorophenoxy)phenyl)methanol and (S)-7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09051325B2
Source datasetuspto-grants-2015_06
ORD IDord-51fb88f3c13d4ead82b24dd92ca55123
Source noteuspto-grants-2015_06