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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2171388Generated: October 26, 2026

7-chloro-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one → 7-((3-fluoro-4-((2-fluoropyridin-4-yl)oxy)benzyl)oxy)-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one

https://huagongshe.com/reaction/2171388

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-chloro-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728345—
Reactant(3-Fluoro-4-((2-fluoropyridin-4-yl)oxy)phenyl)methanolHCID 86728364—
Product7-((3-fluoro-4-((2-fluoropyridin-4-yl)oxy)benzyl)oxy)-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728363—

Reaction Steps

The title compound was prepared by a procedure similar to that described for E9 starting from (3-fluoro-4-((2-fluoropyridin-4-yl)oxy)phenyl)methanol and 7-chloro-1,2,2-trimeth-yl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09051325B2
Source datasetuspto-grants-2015_06
ORD IDord-8a6429afdf93424fb5c131ba9e447212
Source noteuspto-grants-2015_06