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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2171391Generated: October 30, 2026

3-(Hydroxymethyl)benzonitrile → (R)-3-(((1,2-dimethyl-5-oxo-1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidin-7-yl)oxy)methyl)benzonitrile

https://huagongshe.com/reaction/2171391

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Hydroxymethyl)benzonitrileHCID 2734677—
Reactant(R)-7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728369—
Product(R)-3-(((1,2-dimethyl-5-oxo-1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidin-7-yl)oxy)methyl)benzonitrileHCID 86728368—

Reaction Steps

The title compound was prepared by a procedure similar to that described for E9 starting from 3-(hydroxymethyl)benzonitrile and (R)-7-chloro-1,2-dimethyl-2,3-dihydroimidaz-o[1,2-c]pyrimidin-5(1H)-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09051325B2
Source datasetuspto-grants-2015_06
ORD IDord-6b732a9aee2942ba834d29ea7cee3234
Source noteuspto-grants-2015_06