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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2171394Generated: November 1, 2026

4-Chloro-3-fluorobenzyl alcohol → 7-((4-chloro-3-fluorobenzyl)oxy)-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one

https://huagongshe.com/reaction/2171394

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-3-fluorobenzyl alcoholHCID 2773611—
Reactant7-chloro-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728345—
Product7-((4-chloro-3-fluorobenzyl)oxy)-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 86728372—

Reaction Steps

The title compound was prepared by a procedure similar to that described for E1 starting from 7-chloro-1,2,2-trimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one and (4-chloro-3-fluorophenyl)methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09051325B2
Source datasetuspto-grants-2015_06
ORD IDord-5b23887ed91c40f1b9181b43484abfb6
Source noteuspto-grants-2015_06