2,3-Difluorobenzyl Alcohol → HCID 86728384, compound

HRID 2171404Notes

Reaction equation

HRID 2171404 reaction equation
Cl[C:2]1[CH:3]=[C:4]2[N:11]([CH:12]([CH3:14])[CH3:13])[C:10]([CH3:16])([CH3:15])[CH2:9][N:5]2[C:6](=[O:8])[N:7]=1.[F:17][C:18]1[C:23]([F:24])=[CH:22][CH:21]=[CH:20][C:19]=1[CH2:25][OH:26]>>[F:17][C:18]1[C:23]([F:24])=[CH:22][CH:21]=[CH:20][C:19]=1[CH2:25][O:26][C:2]1[CH:3]=[C:4]2[N:11]([CH:12]([CH3:14])[CH3:13])[C:10]([CH3:16])([CH3:15])[CH2:9][N:5]2[C:6](=[O:8])[N:7]=1

Participants

3

Reactant 2

HCID 4471532,3-Difluorobenzyl AlcoholHCID 86728333HCID 86728333, compound

Product 1

HCID 86728384HCID 86728384, compound

Procedure

The title compound was prepared by a procedure similar to that described for E1 starting from 7-chloro-1-isopropyl-2,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one and (2,3-difluorophenyl)methanol.

Sources & evidence

ORD record
ord-54d1c03246144d4ca9216cf3c8131c47
Source dataset
uspto-grants-2015_06
Patent number
US09051325B2

Reaction notes

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