HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4,5-Trifluorobenzyl alcohol → (S)-2-methyl-7-((3,4,5-trifluorobenzyl)oxy)-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4,5-Trifluorobenzyl alcohol | HCID 2777040 | — |
| Reactant | (S)-tert-butyl 7-chloro-2-methyl-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate | HCID 86728347 | — |
| Product | (S)-2-methyl-7-((3,4,5-trifluorobenzyl)oxy)-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one | HCID 86728387 | — |
Reaction Steps
The title compound was prepared by a procedure similar to that described for E1 starting from (3,4,5-trifluorophenyl)methanol and (S)-tert-butyl 7-chloro-2-methyl-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09051325B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-4ff783b7b5ad4191a17fb3db87ec473d |
| Source note | uspto-grants-2015_06 |