2,3-Difluorobenzyl Alcohol → HCID 86728404, compound

HRID 2171422Notes

Reaction equation

HRID 2171422 reaction equation
Cl[C:2]1[CH:3]=[C:4]2[N:11]([CH2:12][CH3:13])[C:10]([CH3:15])([CH3:14])[CH2:9][N:5]2[C:6](=[O:8])[N:7]=1.[F:16][C:17]1[C:22]([F:23])=[CH:21][CH:20]=[CH:19][C:18]=1[CH2:24][OH:25]>>[F:16][C:17]1[C:22]([F:23])=[CH:21][CH:20]=[CH:19][C:18]=1[CH2:24][O:25][C:2]1[CH:3]=[C:4]2[N:11]([CH2:12][CH3:13])[C:10]([CH3:15])([CH3:14])[CH2:9][N:5]2[C:6](=[O:8])[N:7]=1

Participants

3

Reactant 2

HCID 4471532,3-Difluorobenzyl AlcoholHCID 86728330HCID 86728330, compound

Product 1

HCID 86728404HCID 86728404, compound

Procedure

The title compound was prepared by a procedure similar to that described for E1 starting from 7-chloro-1-ethyl-2,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one and (2,3-difluorophenyl)methanol.

Sources & evidence

ORD record
ord-2f56aa88674d447593400f1e187889ac
Source dataset
uspto-grants-2015_06
Patent number
US09051325B2

Reaction notes

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