3-(Hydroxymethyl)benzonitrile → HCID 86728408, compound

HRID 2171425Notes

Reaction equation

HRID 2171425 reaction equation
[OH:1][CH2:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[C:6]#[N:7].Cl[C:12]1[CH:13]=[C:14]2[N:21]([CH:22]3[CH2:24][CH2:23]3)[CH2:20][CH2:19][N:15]2[C:16](=[O:18])[N:17]=1>>[CH:22]1([N:21]2[C:14]3[N:15]([C:16](=[O:18])[N:17]=[C:12]([O:1][CH2:2][C:3]4[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=4)[C:6]#[N:7])[CH:13]=3)[CH2:19][CH2:20]2)[CH2:24][CH2:23]1

Participants

3

Reactant 2

HCID 27346773-(Hydroxymethyl)benzonitrileHCID 86728325HCID 86728325, compound

Product 1

HCID 86728408HCID 86728408, compound

Procedure

The title compound was prepared by a procedure similar to that described for E9 starting from 3-(hydroxymethyl)benzonitrile and 7-chloro-1-cyclopropyl-2,3-dihydroimidazo-[1,2-c]pyrimidin-5(1H)-one.

Sources & evidence

ORD record
ord-6693dc5c9c1e4ee689b5bd14363cb88a
Source dataset
uspto-grants-2015_06
Patent number
US09051325B2

Reaction notes

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