3-(Hydroxymethyl)benzonitrile → HCID 86728410, compound

HRID 2171427Notes

Reaction equation

HRID 2171427 reaction equation
[OH:1][CH2:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[C:6]#[N:7].Cl[C:12]1[CH:13]=[C:14]2[N:21]([CH3:22])[C@@H:20]([CH3:23])[CH2:19][N:15]2[C:16](=[O:18])[N:17]=1>>[CH3:22][N:21]1[C:14]2[N:15]([C:16](=[O:18])[N:17]=[C:12]([O:1][CH2:2][C:3]3[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=3)[C:6]#[N:7])[CH:13]=2)[CH2:19][C@@H:20]1[CH3:23]

Participants

3

Reactant 2

HCID 27346773-(Hydroxymethyl)benzonitrileHCID 86728322(S)-7-chloro-1,2-dimethyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one

Product 1

HCID 86728410HCID 86728410, compound

Procedure

The title compound was prepared by a procedure similar to that described for E9 starting from 3-(hydroxymethyl)benzonitrile and (S)-7-chloro-1,2-dimethyl-2,3-dihydroimidaz-o[1,2-c]pyrimidin-5(1H)-one.

Sources & evidence

ORD record
ord-6a79abc082e54ef080aa93f0d1669396
Source dataset
uspto-grants-2015_06
Patent number
US09051325B2

Reaction notes

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